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hopF2 hopF2 hopAB2 hopAB2 shcF shcF hopU1 hopU1 hopAI1 hopAI1 fliC fliC hopAO1 hopAO1 hopM1 hopM1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hopF2Type III effector HopF2; This gene has an isoleucine start. Previously known as HolPtoAD (PMID11872842; Guttman et al, 2002) and HopPtoF (PMID11854524; Fouts et al, 2002); see PMID:20190049 for expression data; similar to GP:7677395; identified by sequence similarity; putative. (204 aa)    
Predicted Functional Partners:
hopAB2
Type III effector HopAB2; Effector protein involved in gene-for-gene resistance in tomato plants. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible plants, acts as a virulence factor by suppressing PCD and HR-based plant immunity. This function requires its E3 ubiquitin ligase activity probably by recruiting E2 enzymes and transferring ubiquitin molecules to cellular proteins involved in regulation of PCD and targeting them for degradation. Also, [...]
      
 0.768
shcF
Type III chaperone protein ShcF; See PMID:20190049 for expression data.
     
 0.733
hopU1
Type III effector HopU1; Previously known as HopPtoS2 (PMID12032338; Petnicki-Ocwieja et al, 2002).
     
 0.724
hopAI1
Type III effector HopAI1; Previously known as HolPtoAI (PMID12615215; Greenberg and Vinatzer, 2003); similar to SP:P21456, GB:M33318, GB:X13897, GB:X13929, GB:X06401, GB:X13930, SP:P11509, SP:P20853, PID:180987, PID:29547, PID:30332, and PID:825700; identified by sequence similarity; putative.
      
 0.717
fliC
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
      
 0.540
hopAO1
Type III effector HopAO1; Effector showing tyrosine-phosphatase activity required for host defense suppression. Functions inside plant cells causing suppression of HR (hypersensitive response), PR1 gene expression and oxidative burst probably by interfering with a MAPK (mitogen-activated protein kinase) pathway. MAPK cascades are known to activate defense- related transcription factors. Inhibits plant pattern-recognition receptors (PRRs) activation.
      
 0.506
hopM1
Type III effector HopM1; Involved in the suppression of basal resistance and promotion of disease symptoms in plants. Mediates the ubiquitination and degradation, via the host proteasome, of a low-abundance immunity- associated protein in Arabidopsis thaliana. May be involved in the inhibition of a host vesicle trafficking pathway.
      
 0.459
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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